Toxicology and Carcinogenesis Studies of C.I. Direct Blue Is (Cas No. 2429-41-5),...Technical Report Series... No.397... U.S. Dept.of Health an Human Services... 1995.

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ContributionsNational Cancer Institute (U.S.)
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Open LibraryOL17698240M

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NTP Toxicology and Carcinogenesis Studies of C.I. Direct Blue (CAS No. ) in F/N Rats and B6C3F1 Mice (Feed Studies). National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. Feb; Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of C.I. direct blue 15 (desalted industrial grade) (CAS no. ) in F/N rats (drinking water studies). [National Toxicology Program (U.S.);]. Toxicology and Carcinogenesis Studies of C.I.

Disperse Blue 1 (A commercial dye containing approximately 50% 1,4,5,8-tetraaminoanthraquinone, and 20% water) (CASRN ) in F/N Rats and B6C3F1 Mice (Feed Studies) Long-Term Carcinogenicity TR PDF (10MB). NTP Toxicology and Carcinogenesis Studies of C.I.

Direct Blue (CAS No. ) in F/N Rats and B6C3F1 Mice (Feed Studies). National Toxicology Program. Natl Toxicol Program Tech Rep Ser,01 Feb Cited by 1 article | PMID: The heterotopic urinary bladder with a communicating reservoir is a potentially useful model for bladder carcinogenesis studies.

To test whether such bladders will develop transitional cell carcinomas after chronic carcinogenic stimuli, 2 carcinogens, MNU and BCPN were instilled repeatedly into the reservoir connected with the heterotopic bladder.

Wexler, in Encyclopedia of Toxicology (Third Edition), Chemical Specific Factual Databanks Chemical Carcinogenesis Research Information System. Chemical Carcinogenesis Research Information System (CCRIS) is a scientifically evaluated and fully referenced data bank, developed by the National Cancer Institute (NCI), but no longer updated.

It contains over. National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of C I. Disperse Blue 1 (A commercial dye containing approximately 50% 1,4,5,8-tetraaminoanthraquinone, and 20% water) (CAS No. ) in F/N Rats and B6C3F1 Mice (Feed Studies) Natl Toxicol Program Tech Rep Ser.

May;; – [Google Scholar]. The epigenetic basis of carcinogenesis is probably the most widely studied epigenetic basis of diseased state. Studies over the last 30 years or so have confirmed that the genome in a cancer cell/tissue is characterized by global (genome-wide) hypomethylation and site-specific promoter hypermethylation.

Although most NTP studies do not use interim sacrifices, in many NTP positive studies in which there was an interim sacrifice at either 12 months (e.g. D&C Yellow 11; NTP TR) or at 15 months (e.g.

3,4-dihydrocoumarin, NTP TR; o-benzyl-p-chlorophenol, NTP TR; C.I. Direct BlueNTP TR ; butyl benzyl phthalate, NTP TR J.E. Klaunig, L.M. Kamendulis, in Comprehensive Toxicology, Direct-acting (activation-independent) carcinogens.

Several carcinogens exist that do not require metabolic activation or modification to induce cancer and are termed direct-acting or activation-independent carcinogens. These chemicals function as ultimate carcinogens (Table 4).

Toxicology and carcinogenesis studies were conducted by administering the dye, C.I. Direct B in drinking water to groups of F/N rats of each sex for 14 days, 13 weeks, or 22 months. Planned as month studies, the month studies were terminated early because of rapidly declining animal survival, which was due primarily to neoplasia.

toxicology and carcinogenesis studies of hc blue no 2,2'((4-((2-hydroxyethyl)amin0)nitrophenyl)imino)bis(ethanol) (cas no. ) in f/n rats and b6c3ft mice (feed studies) u.s. department of health and human services public health service national institutes of health. NATIONAL TOXICOLOGY PROGRAM Technical Report Series No.

TOXICOLOGY AND CARCINOGENESIS. STUDIES OF. TRIS(2-ETHYLHEXYL)PHOSPHATE (CASNO. ) IN F/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES. Public Health Service National Institutes. Health. NTP technical report on the toxicology and carcinogenesis studies of C.I.

direct blue (CAS no. ) in F/N rats and B6C3F₁ mice (feed studies) Author: National Toxicology Program (U.S.). Toxicology and Carcinogenesis Studies of C.I. Direct Blue 15 (CAS No.

) in F/N Rats and B6C3F1 Mice (Drinking Water Studies). NTP Technical Report Series No. NTIS Publication No.

US Department of Health and. Author(s): National Toxicology Program (U.S.) Title(s): NTP technical report on the toxicology and carcinogenesis studies of C.I.

direct blue 15 (desalted industrial grade) (CAS no) in F/N rats (drinking water studies)/ National Toxicology Program. C.I. Pigment Red 23 is a bluish red commercial dye used as a coloring agent in paints, inks, rubber, plastics, lacquers, and paper.

Toxicology and carcinogenicity studies were conducted by feeding groups of rats and mice diets containing C.I. Pigment Red 23 (greater than 96% pure) for 17 days, 13 we. Toxicology & Carcinogenesis Studies of C.I. Direct Blue in F/N Rats and B6C3F1 Mice Technical Report Series No.

() NIH Publication No. U.S. Department of Health and Human Services, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC NTP. C.I. Direct blue (). Chemical Effects in Biological Systems (CEBS).

Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed ht. NTP. TR C.I. Direct blue (). Chemical Effects in Biological Systems (CEBS).

Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed   The following investigators are involved in Toxicology/Carcinogenesis projects: Gregg Dinse, Grace Kissling, Keith Shockley. Examples of three general areas of research and various special topics are given below: Rodent Cancer Bioassays.

Improved statistical analysis of tumor data; Incorporation and analysis of historical control data. Get this from a library.

NTP technical report on the toxicology and carcinogenesis studies of C.I. direct blue (CAS no. ): in F/N rats and B6C3F₁ mice: (feed studies). [National Toxicology Program (U.S.);]. Author(s): National Toxicology Program (U.S.) Title(s): NTP technical report on the toxicology and carcinogenesis studies of C.I.

direct blue (CAS no. ): in F/N rats and B6C3F₁ mice: (feed studies)[microform] / National Toxicology Program. NTP technical report on the toxicology and carcinogenesis studies of alpha-Methyldopa sesquihydrate (CAS no. ) in F/N rats and B6C3F₁ mice (feed studies) [microform] / June K.

Dunnick, Chemical Manager National Toxicology Program, U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health. There are no human carcinogenicity studies of C.I.

Direct Blue Increases in urinary bladder neoplasms in humans exposed to other benzidine-based dyes have been observed in epidemiological studies. National Toxicology Program (NTP, b). Toxicology and Carcinogenesis Studies of C.I. Direct Blue (CAS No.

) in F/N Rats and B6C3F1 Mice (Feed Studies). NTP Technical Report Series No. NTIS Publication No. US Department of Health and Human Services, NTP, Research Triangle Park, NC.

Toxicology and carcinogenesis studies of a nondecolorized [corrected] whole leaf extract of Aloe barbadensis Miller (Aloe vera) in F/N rats and B6C3F1 mice (drinking water study). Boudreau MD, Beland FA, Nichols JA, Pogribna M.

Erratum in Natl Toxicol Program Tech Rep Ser. Aug;() NTP Toxicology and Carcinogenesis Studies of 1,4-Dichlorobenzene (CAS No. ) in F/N Rats and B6C3F1 Mice (Gavage Studies). National Toxicology Program. 1,4-Dichlorobenzene is commonly used as a space deodorant in toilets and for moth control.

Because of its extensive production and use and the absence of carcinogenicity data. toxicology and carcinogenesis study of chloral hydrate (ad libitum and dietary controlled) (cas no. ) in male b6c3f 1 mice (gavage study) national toxicology program p.o. box research triangle park, nc december ntp tr nih publication no.

u.s. Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M. Review of toxicity studies and other toxicology information results in an estimate of the acceptable daily intake (ADI) for the direct food additive or color additive used in.

Industrial grade C.I. Direct Blue was selected for study because of its widespread use. Because of the high salt content, the dye was desalted prior to use. Toxicology and carcinogenesis studies were conducted by administering C.I. Direct Blue in feed to groups of male and female F/N rats and B6C3F1 mice for 14 days, 13 weeks, and 2.

An illustration of an open book. Books. An illustration of two cells of a film strip. Video An illustration of an audio speaker. Full text of "NTP technical report on the toxicology and carcinogenesis studies of benzethonium chloride (dermal studies)" See other formats.

Toxicology and carcinogenesis studies of dietary titanium dioxide‐coated mica in male and female Fischer rats. Journal of Toxicology and Environmental Health: Vol. 29. People have raised questions about the safety and effectiveness of water fluoridation since it first began.

Over the years, many studies have looked at the possible link between fluoride and cancer. Some of the controversy about the possible link stems from a study of lab animals reported by the US National Toxicology Program (NTP) in All members in good standing of the Society of Toxicology shall become members of the Carcinogenesis Specialty Section upon payment of Specialty dues.

A member of the Carcinogenesis Specialty Section will be dropped from membership if dues are not paid on an annual basis or if he or she is not a member in good standing of the Society of Toxicology. An illustration of an open book. Books. An illustration of two cells of a film strip.

Video An illustration of an audio speaker. Full text of "NTP technical report on the toxicology and carcinogenesis studies of nitrofurantoin (feed studies)" See other formats. Get this from a library. week subchronic toxicity studies: direct blue 6, direct bl and direct brown 95 dyes. [National Cancer Institute (U.S.).

Toxicology and Carcinogenesis Studies of C.I. Direct Blue 15 in F/N Rats (Drinking Water Studies), CAS No. Technical Report Series No.

pp. National Institutes of Health, Research Triangle Park, North Carolina. Google Scholar. Full text of "NTP technical report on the toxicology and carcinogenesis studies of 4-vinylcyclohexene diepoxide (CAS no. ) in F/N rats and B6C3F1 mice (dermal studies)" See other formats.

Toxicology & Carcinogenesis Studies of C.I. Disperse Blue 1) in F/N Rats and B6C3F1 Mice (Feed Studies). Technical Report Series No. () NIH Publication No. U.S. Department of Health and Human Services, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC Therefore, additional toxicology and carcinogenesis studies were conducted in F/N rats by administering hexachloroethane (approximately 99% pure) in corn oil by gavage to groups of males and females for 16 days, 13 weeks, or 2 years.

Genetic toxicology studies were conducted in Salmonella typhimurium and in Chinese hamster ovary (CHO) cells.NTP technical report on the toxicology and carcinogenesis studies of rotenone (CAS no. ) in F/N rats and B6C3F́ mice (feed studies) by National Toxicology Program (U.S.).

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